Identification of TCR Vβ11-2-Dβ1-Jβ1-1 T cell clone specific for WT1 peptides using high-throughput TCRβ gene sequencing

We previously identified a TCR Vβ21 T cell clone which was specific to CML patients, and demonstrated that TCR Vα13/β21 gene-modified CD3(+) T cells had specific cytotoxicity for HLA-A11(+) K562 cells. However, it remains unclear which antigen is specifically recognized by the TCR Vβ21 T cell clone....

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Detalles Bibliográficos
Autores principales: Zhang, Yikai, Xu, Ling, Chen, Shaohua, Zha, Xianfeng, Wei, Wei, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570921/
https://www.ncbi.nlm.nih.gov/pubmed/31223481
http://dx.doi.org/10.1186/s40364-019-0163-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570921/
https://www.ncbi.nlm.nih.gov/pubmed/31223481
http://dx.doi.org/10.1186/s40364-019-0163-1

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