The p52 isoform of SHC1 is a key driver of breast cancer initiation

BACKGROUND: SHC1 proteins (also called SHCA) exist in three functionally distinct isoforms (p46SHC, p52SHC, and p66SHC) that serve as intracellular adaptors for several key signaling pathways in breast cancer. Despite the broad evidence implicating SHC1 gene products as a central mediator of breast...

Descripción completa

Detalles Bibliográficos
Autores principales: Wright, Kevin D., Miller, Bradley S., El-Meanawy, Sarah, Tsaih, Shirng-Wern, Banerjee, Anjishnu, Geurts, Aron M., Sheinin, Yuri, Sun, Yunguang, Kalyanaraman, Balaraman, Rui, Hallgeir, Flister, Michael J., Sorokin, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570928/
https://www.ncbi.nlm.nih.gov/pubmed/31202267
http://dx.doi.org/10.1186/s13058-019-1155-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570928/
https://www.ncbi.nlm.nih.gov/pubmed/31202267
http://dx.doi.org/10.1186/s13058-019-1155-7

Ejemplares similares