Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants

BACKGROUND: Extensive genome rearrangements, known as chromothripsis, have been recently identified in several cancer types. Chromothripsis leads to complex structural variants (cSVs) causing aberrant gene expression and the formation of de novo fusion genes, which can trigger cancer development, or...

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Detalles Bibliográficos
Autores principales: Hynst, Jakub, Plevova, Karla, Radova, Lenka, Bystry, Vojtech, Pal, Karol, Pospisilova, Sarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571010/
https://www.ncbi.nlm.nih.gov/pubmed/31223530
http://dx.doi.org/10.7717/peerj.7071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571010/
https://www.ncbi.nlm.nih.gov/pubmed/31223530
http://dx.doi.org/10.7717/peerj.7071

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