The effects of PTPN2 loss on cell signalling and clinical outcome in relation to breast cancer subtype

PURPOSE: The protein tyrosine phosphatase PTPN2 dephosphorylates several tyrosine kinases in cancer-related signalling pathways and is thought to be a tumour suppressor. As PTPN2 is not frequently studied in breast cancer, we aimed to explore the role of PTPN2 and the effects of its loss in breast c...

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Detalles Bibliográficos
Autores principales: Veenstra, Cynthia, Karlsson, Elin, Mirwani, Sanam Mirwani, Nordenskjöld, Bo, Fornander, Tommy, Pérez-Tenorio, Gizeh, Stål, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article – Clinical Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571101/
https://www.ncbi.nlm.nih.gov/pubmed/31025094
http://dx.doi.org/10.1007/s00432-019-02918-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571101/
https://www.ncbi.nlm.nih.gov/pubmed/31025094
http://dx.doi.org/10.1007/s00432-019-02918-y

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