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Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely unknown. We previously reported that the generation of hemo...

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Detalles Bibliográficos
Autores principales: Gomes, Andreia M., Kurochkin, Ilia, Chang, Betty, Daniel, Michael, Law, Kenneth, Satija, Namita, Lachmann, Alexander, Wang, Zichen, Ferreira, Lino, Ma’ayan, Avi, Chen, Benjamin K., Papatsenko, Dmitri, Lemischka, Ihor R., Moore, Kateri A., Pereira, Carlos-Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571141/
https://www.ncbi.nlm.nih.gov/pubmed/30517869
http://dx.doi.org/10.1016/j.celrep.2018.11.032