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Relevance of HLA-DQB1*02 Allele in the Genetic Predisposition of Children with Celiac Disease: Additional Cues from a Meta-Analysis

Background and Objectives: Celiac disease (CD) is a multifactorial immune-mediated disorder, triggered by the ingestion of gluten in genetically-predisposed subjects carrying MHC-DQ2 and -DQ8 heterodimers, which are encoded by four HLA-DQ allelic variants, overall. This meta-analysis aims at providi...

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Detalles Bibliográficos
Autores principales: Capittini, Cristina, De Silvestri, Annalisa, Rebuffi, Chiara, Tinelli, Carmine, Poddighe, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571594/
https://www.ncbi.nlm.nih.gov/pubmed/31121940
http://dx.doi.org/10.3390/medicina55050190