Sex-Dependence in the Effect of Pharmaceutical Excipients: Polyoxyethylated Solubilising Excipients Increase Oral Drug Bioavailability in Male but Not Female Rats

It is known that males and females respond differently to medicines and that differences in drug behaviour are due to inter-individual variability and sex specificity. In this work, we have examined the influence of pharmaceutical excipients on drug bioavailability in males and females. Using a rat...

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Detalles Bibliográficos
Autores principales: Mai, Yang, Dou, Liu, Madla, Christine M., Murdan, Sudaxshina, Basit, Abdul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571596/
https://www.ncbi.nlm.nih.gov/pubmed/31083453
http://dx.doi.org/10.3390/pharmaceutics11050228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571596/
https://www.ncbi.nlm.nih.gov/pubmed/31083453
http://dx.doi.org/10.3390/pharmaceutics11050228

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