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Sex-Dependence in the Effect of Pharmaceutical Excipients: Polyoxyethylated Solubilising Excipients Increase Oral Drug Bioavailability in Male but Not Female Rats
It is known that males and females respond differently to medicines and that differences in drug behaviour are due to inter-individual variability and sex specificity. In this work, we have examined the influence of pharmaceutical excipients on drug bioavailability in males and females. Using a rat...
Autores principales: | Mai, Yang, Dou, Liu, Madla, Christine M., Murdan, Sudaxshina, Basit, Abdul W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571596/ https://www.ncbi.nlm.nih.gov/pubmed/31083453 http://dx.doi.org/10.3390/pharmaceutics11050228 |
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