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Computer Modeling of Alzheimer’s Disease—Simulations of Synaptic Plasticity and Memory in the CA3-CA1 Hippocampal Formation Microcircuit

This paper aims to present computer modeling of synaptic plasticity and memory in the CA3-CA1 hippocampal formation microcircuit. The computer simulations showed a comparison of a pathological model in which Alzheimer’s disease (AD) was simulated by synaptic degradation in the hippocampus and contro...

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Detalles Bibliográficos
Autores principales: Świetlik, Dariusz, Białowąs, Jacek, Moryś, Janusz, Klejbor, Ilona, Kusiak, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571632/
https://www.ncbi.nlm.nih.gov/pubmed/31108977
http://dx.doi.org/10.3390/molecules24101909