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Multiclass Classifier for P-Glycoprotein Substrates, Inhibitors, and Non-Active Compounds
P-glycoprotein (P-gp) is a transmembrane protein that actively transports a wide variety of chemically diverse compounds out of the cell. It is highly associated with the ADMET (absorption, distribution, metabolism, excretion and toxicity) properties of drugs/drug candidates and contributes to decre...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571636/ https://www.ncbi.nlm.nih.gov/pubmed/31130601 http://dx.doi.org/10.3390/molecules24102006 |