Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Intrinsically disordered proteins (IDPs) can form functional oligomers and in some cases, insoluble disease related aggregates. It is therefore vital to understand processes and mechanisms that control pathway distribution. Divalent cations including Zn(2+) can initiate IDP oligomerisation through t...

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Detalles Bibliográficos
Autores principales: Cragnell, Carolina, Staby, Lasse, Lenton, Samuel, Kragelund, Birthe B., Skepö, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571702/
https://www.ncbi.nlm.nih.gov/pubmed/31052346
http://dx.doi.org/10.3390/biom9050168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571702/
https://www.ncbi.nlm.nih.gov/pubmed/31052346
http://dx.doi.org/10.3390/biom9050168

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