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Consecutive Prostate Cancer Specimens Revealed Increased Aldo–Keto Reductase Family 1 Member C3 Expression with Progression to Castration-Resistant Prostate Cancer

Aldo-keto reductase family 1 member C3 (AKR1C3) is an enzyme in the steroidogenesis pathway, especially in formation of testosterone and dihydrotestosterone, and is believed to have a key role in promoting prostate cancer (PCa) progression, particularly in castration-resistant prostate cancer (CRPC)...

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Detalles Bibliográficos
Autores principales: Miyazaki, Yu, Teramoto, Yuki, Shibuya, Shinsuke, Goto, Takayuki, Okasho, Kosuke, Mizuno, Kei, Uegaki, Masayuki, Yoshikawa, Takeshi, Akamatsu, Shusuke, Kobayashi, Takashi, Ogawa, Osamu, Inoue, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571723/
https://www.ncbi.nlm.nih.gov/pubmed/31052459
http://dx.doi.org/10.3390/jcm8050601