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Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma

A paucity of advances in the development of novel therapeutic agents for squamous cell carcinomas of the head and neck, oral cavity (OSCC) and oropharynx, has stagnated disease free survival rates over the past two decades. Although immunotherapies targeted against checkpoint inhibitors such as PD-1...

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Detalles Bibliográficos
Autores principales: Shah O’Brien, Priyanka, Xi, Yue, Miller, Justin R., Brownell, Amy L., Zeng, Qinghua, Yoo, George H., Garshott, Danielle M., O’Brien, Matthew B., Galinato, Anthony E., Cai, Peter, Narula, Neha, Callaghan, Michael U., Kaufman, Randal J., Fribley, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571807/
https://www.ncbi.nlm.nih.gov/pubmed/31064122
http://dx.doi.org/10.3390/jcm8050611