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Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer

Aberrant activation of signal transducer and activator of transcription 3 (STAT3) has been documented in various malignancies including triple-negative breast cancers (TNBCs). The STAT3 transcription factor can regulate the different important hallmarks of tumor cells, and thus, targeting it can be...

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Detalles Bibliográficos
Autores principales: Ko, Hyejin, Lee, Jong Hyun, Kim, Hyun Su, Kim, Taewoo, Han, Young Taek, Suh, Young-Ger, Chun, Jaemoo, Kim, Yeong Shik, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571922/
https://www.ncbi.nlm.nih.gov/pubmed/31058868
http://dx.doi.org/10.3390/biom9050170