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Chenodeoxycholic Acid Ameliorates AlCl(3)-Induced Alzheimer’s Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats

Insulin resistance is a major risk factor for Alzheimer’s disease (AD). Chenodeoxycholic acid (CDCA) and synthetic Farnesoid X receptor (FXR) ligands have shown promising outcomes in ameliorating insulin resistance associated with various medical conditions. This study aimed to investigate whether C...

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Detalles Bibliográficos
Autores principales: Bazzari, Firas H., Abdallah, Dalaal M., El-Abhar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571973/
https://www.ncbi.nlm.nih.gov/pubmed/31137621
http://dx.doi.org/10.3390/molecules24101992