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Chenodeoxycholic Acid Ameliorates AlCl(3)-Induced Alzheimer’s Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats
Insulin resistance is a major risk factor for Alzheimer’s disease (AD). Chenodeoxycholic acid (CDCA) and synthetic Farnesoid X receptor (FXR) ligands have shown promising outcomes in ameliorating insulin resistance associated with various medical conditions. This study aimed to investigate whether C...
Autores principales: | Bazzari, Firas H., Abdallah, Dalaal M., El-Abhar, Hanan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571973/ https://www.ncbi.nlm.nih.gov/pubmed/31137621 http://dx.doi.org/10.3390/molecules24101992 |
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