Phase 1 repolarization rate defines Ca(2+) dynamics and contractility on intact mouse hearts

In the heart, Ca(2+) influx through L-type Ca(2+) channels triggers Ca(2+) release from the sarcoplasmic reticulum. In most mammals, this influx occurs during the ventricular action potential (AP) plateau phase 2. However, in murine models, the influx through L-type Ca(2+) channels happens in early...

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Detalles Bibliográficos
Autores principales: López Alarcón, María Micaela, Rodríguez de Yurre, Ainhoa, Felice, Juan Ignacio, Medei, Emiliano, Escobar, Ariel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571993/
https://www.ncbi.nlm.nih.gov/pubmed/31000581
http://dx.doi.org/10.1085/jgp.201812269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571993/
https://www.ncbi.nlm.nih.gov/pubmed/31000581
http://dx.doi.org/10.1085/jgp.201812269

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