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Phase 1 repolarization rate defines Ca(2+) dynamics and contractility on intact mouse hearts
In the heart, Ca(2+) influx through L-type Ca(2+) channels triggers Ca(2+) release from the sarcoplasmic reticulum. In most mammals, this influx occurs during the ventricular action potential (AP) plateau phase 2. However, in murine models, the influx through L-type Ca(2+) channels happens in early...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571993/ https://www.ncbi.nlm.nih.gov/pubmed/31000581 http://dx.doi.org/10.1085/jgp.201812269 |