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Agonists that stimulate secretion promote the recruitment of CFTR into membrane lipid microdomains

The cystic fibrosis transmembrane conductance regulator (CFTR) is a tightly regulated anion channel that mediates secretion by epithelia and is mutated in the disease cystic fibrosis. CFTR forms macromolecular complexes with many proteins; however, little is known regarding its associations with mem...

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Detalles Bibliográficos
Autores principales: Abu-Arish, Asmahan, Pandžić, Elvis, Kim, Dusik, Tseng, Hsin Wei, Wiseman, Paul W., Hanrahan, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572005/
https://www.ncbi.nlm.nih.gov/pubmed/31048413
http://dx.doi.org/10.1085/jgp.201812143