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Synthesis and Evaluation of Antidepressant Activities of 5-Aryl-4,5-dihydrotetrazolo [1,5-a]thieno[2,3-e]pyridine Derivatives

In this study, we synthetized a series of 5-aryl-4,5-dihydrotetrazolo[1,5-a]thieno[2,3-e]pyridine derivatives containing tetrazole and other heterocycle substituents, i.e., triazole, methyltriazole, and triazolone. The forced swim test (FST) and tail suspension test (TST) were used to evaluate the a...

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Detalles Bibliográficos
Autores principales: Wang, Shiben, Liu, Hui, Wang, Xuekun, Lei, Kang, Li, Guangyong, Quan, Zheshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572050/
https://www.ncbi.nlm.nih.gov/pubmed/31091808
http://dx.doi.org/10.3390/molecules24101857