Cargando…

Synthesis and Evaluation of Antidepressant Activities of 5-Aryl-4,5-dihydrotetrazolo [1,5-a]thieno[2,3-e]pyridine Derivatives

In this study, we synthetized a series of 5-aryl-4,5-dihydrotetrazolo[1,5-a]thieno[2,3-e]pyridine derivatives containing tetrazole and other heterocycle substituents, i.e., triazole, methyltriazole, and triazolone. The forced swim test (FST) and tail suspension test (TST) were used to evaluate the a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shiben, Liu, Hui, Wang, Xuekun, Lei, Kang, Li, Guangyong, Quan, Zheshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572050/ https://www.ncbi.nlm.nih.gov/pubmed/31091808 http://dx.doi.org/10.3390/molecules24101857

Ejemplares similares

Synthesis of some new Thieno[2,3-b]pyridines, Pyrimidino[4',5':4,5]thieno[2,3-b]pyridine and Pyridines Incorporating 5-Bromobenzofuran-2-yl Moiety
por: Abdelriheem, Nadia Abdelhamed, et al.
Publicado: (2015)

8-Chloro-5,5-dimethyl-5,6-dihydrotetrazolo[1,5-c]quinazoline
por: Fun, Hoong-Kun, et al.
Publicado: (2010)

Pyridine-Based Heterocycles. Synthesis of New Pyrido [4',3':4,5]thieno[2,3-d]pyrimidines and Related Heterocycles
por: El-Kashef, Hussein, et al.
Publicado: (2010)

In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines
por: Tkachenko, Irina G, et al.
Publicado: (2019)

Crystal structure of (S)-5,7-diphenyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine
por: Price, Ivy K., et al.
Publicado: (2015)

Crystal structure of 5,7-diphenyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine
por: Price, Ivy K., et al.
Publicado: (2015)

N-(4-Chlorophenyl)-5-(4,5-dihydro-1H-imidazol-2-yl)thieno[2,3-b]pyridin-4-amine
por: Bernardino, Alice M. R., et al.
Publicado: (2012)

Synthesis of 1,3,4-oxadiazoles derivatives with antidepressant activity and their binding to the 5-HT(1A) receptor
por: Wang, Shiben, et al.
Publicado: (2020)

Inhibition of protein kinases by anticancer DNA intercalator, 4-butylaminopyrimido[4′,5′:4,5]thieno(2,3-b)quinoline
por: Rohit Kumar, HeggoduG., et al.
Publicado: (2017)

Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents
por: Islam, Farhana, et al.
Publicado: (2022)

Design, Synthesis, and Biological Activity of Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Anti-Inflammatory Agents
por: Zhang, Yuan, et al.
Publicado: (2017)

5-Bromo-1H-thieno[2,3-d]imidazole
por: Wang, Fen, et al.
Publicado: (2010)

Ethyl 7-(4-bromophenyl)-5-trifluoromethyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate
por: Shen, Shi-De, et al.
Publicado: (2010)

2-Chloro-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)ethanone
por: Yang, Chuan-Wei, et al.
Publicado: (2010)

Design, Synthesis, and In Vivo and In Silico Evaluation of Coumarin Derivatives with Potential Antidepressant Effects
por: Wang, Xuekun, et al.
Publicado: (2021)

Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives
por: Krause, Malwina, et al.
Publicado: (2017)

Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
por: Meng, Shuang-Ming, et al.
Publicado: (2010)

Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione
por: Šafarik, Jelena Blažević, et al.
Publicado: (2005)

GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents
por: Zafar, Ayesha, et al.
Publicado: (2017)

Synthesis and Anti-Proliferative Activity of 5-Benzoyl and 5-Benzylhydroxy Derivatives of 3-Amino-2-Arylcarboxamido-Thieno[2-3-b]Pyridines
por: Morphet, Bailey, et al.
Publicado: (2023)

6-Benzyl-2-[(triphenyl-λ(5)-phosphanylidene)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile
por: Chen, Hong, et al.
Publicado: (2011)

Design, synthesis and evaluation of amino-3,5-dicyanopyridines and thieno[2,3-b]pyridines as ligands of adenosine A(1) receptors for the potential treatment of epilepsy
por: Nkomba, Gaofenngwe, et al.
Publicado: (2022)

Thieno[2,3-b]Pyridine Derivative Targets Epithelial, Mesenchymal and Hybrid CD15s(+) Breast Cancer Cells
por: Marijan, Sandra, et al.
Publicado: (2021)

9-Furfurylidene-2,3-dimethyl-6,7,8,9-tetrahydro-4H-thieno[2′,3′:4,5]pyrimidino[1,2-a]pyridin-4-one
por: Bozorov, Khurshed A., et al.
Publicado: (2010)

Discovery of 4,5-Dihydro-1H-thieno[2′,3′:2,3]thiepino [4,5-c]pyrazole-3-carboxamide Derivatives as the Potential Epidermal Growth Factor Receptors for Tyrosine Kinase Inhibitors
por: Ke, Jia, et al.
Publicado: (2018)

Synthesis, solid-state fluorescence properties, and computational analysis of novel 2-aminobenzo[4,5]thieno[3,2-d]pyrimidine 5,5-dioxides
por: Yokota, Kenichirou, et al.
Publicado: (2012)

4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABA(A) Receptor Subtype
por: Crocetti, Letizia, et al.
Publicado: (2023)

3-(Propylthio)propane-1-sulfonic acid immobilized on functionalized magnetic nanoparticles as an efficient catalyst for one-pot synthesis of dihydrotetrazolo[1,5-a]pyrimidine and tetrahydrotetrazolo[5,1-b]quinazolinone derivatives
por: Karimi, Fatemeh, et al.
Publicado: (2022)

Targeted Synthesis and Study of Anti-tyrosinase Activity of 2-Substituted Tetrahydrobenzo[4,5]Thieno[2,3-d]Pyrimidine-4(3H)-One
por: Chiriapkin, Alexey, et al.
Publicado: (2022)

Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines
por: Masch, Andreas, et al.
Publicado: (2019)

Tethered Aryl Groups Increase the Activity of Anti-Proliferative Thieno[2,3-b]Pyridines by Targeting a Lipophilic Region in the Active Site of PI-PLC
por: Haverkate, Natalie A., et al.
Publicado: (2021)

Studies on the Reactivity of (9-Methyl-5,6-dihydronaphtho[1′,2′:4,5]-thieno[2,3-d]pyrimidin-11-yl)hydrazine Towards Some Reagents for Biological Evaluation
por: Rashad, Aymn E., et al.
Publicado: (2010)

3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbonitrile
por: Zeng, Xiu-Xiu, et al.
Publicado: (2009)

Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents
por: Zafar, Ayesha, et al.
Publicado: (2018)

Disruption of Crystal Packing in Thieno[2,3-b]pyridines Improves Anti-Proliferative Activity
por: Haverkate, Natalie A., et al.
Publicado: (2022)

Synthesis of 3-aryl-1-phosphinoimidazo[1,5-a]pyridine ligands for use in Suzuki–Miyaura cross-coupling reactions
por: Tran, Ryan Q., et al.
Publicado: (2021)

2-Methyl-4-oxo-6,7,8,9-tetrahydrothieno[2′,3′:4,5]pyrimidino[1,2-a]pyridine-3-carboxylic acid
por: Elmuradov, Burkhon Zh., et al.
Publicado: (2011)

7-Benzyl-3-(4-chlorophenyl)-2-isobutylamino-5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
por: Chen, Hong, et al.
Publicado: (2012)

5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
por: Yang, Jing, et al.
Publicado: (2012)

5-(2-Cyanobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
por: Xie, Xiao-Shuai, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vvb458hodqn8mnp49uoim3ba3i