Amphiphilic Block Copolymer Poly (Acrylic Acid)-B-Polycaprolactone as a Novel pH-sensitive Nanocarrier for Anti-Cancer Drugs Delivery: In-vitro and In-vivo Evaluation

Gambogenic acid (GNA) has been demonstrated with outstanding antitumor activity as a potential antitumor drug in recent years. However, the low solubility and deficient bioavailability of GNA seriously hinder its practical application in the clinic area. In this study, a novel amphiphilic block copo...

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Detalles Bibliográficos
Autores principales: Liu, Huanhuan, Chen, Hong, Cao, Fuhu, Peng, Daiyin, Chen, Weidong, Zhang, Chuanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572073/
https://www.ncbi.nlm.nih.gov/pubmed/31067730
http://dx.doi.org/10.3390/polym11050820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572073/
https://www.ncbi.nlm.nih.gov/pubmed/31067730
http://dx.doi.org/10.3390/polym11050820

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