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Amphiphilic Block Copolymer Poly (Acrylic Acid)-B-Polycaprolactone as a Novel pH-sensitive Nanocarrier for Anti-Cancer Drugs Delivery: In-vitro and In-vivo Evaluation
Gambogenic acid (GNA) has been demonstrated with outstanding antitumor activity as a potential antitumor drug in recent years. However, the low solubility and deficient bioavailability of GNA seriously hinder its practical application in the clinic area. In this study, a novel amphiphilic block copo...
Autores principales: | Liu, Huanhuan, Chen, Hong, Cao, Fuhu, Peng, Daiyin, Chen, Weidong, Zhang, Chuanling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572073/ https://www.ncbi.nlm.nih.gov/pubmed/31067730 http://dx.doi.org/10.3390/polym11050820 |
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