Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway

Increased glycolysis in tumor cells is associated with increased risk of tumor progression and mortality. Therefore, disruption of glycolysis, one of the main sources of cellular energy supply, can serve as a target for suppressing tumor growth and progression. Of note, hexokinase-2 (HK2) plays vita...

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Detalles Bibliográficos
Autores principales: Wu, Hongyan, Pan, Lanlan, Gao, Cuixiang, Xu, Hongtao, Li, Yanping, Zhang, Lihu, Ma, Linwei, Meng, Li, Sun, Xiulan, Qin, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572074/
https://www.ncbi.nlm.nih.gov/pubmed/31137633
http://dx.doi.org/10.3390/molecules24101993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572074/
https://www.ncbi.nlm.nih.gov/pubmed/31137633
http://dx.doi.org/10.3390/molecules24101993

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