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Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway
Increased glycolysis in tumor cells is associated with increased risk of tumor progression and mortality. Therefore, disruption of glycolysis, one of the main sources of cellular energy supply, can serve as a target for suppressing tumor growth and progression. Of note, hexokinase-2 (HK2) plays vita...
Autores principales: | Wu, Hongyan, Pan, Lanlan, Gao, Cuixiang, Xu, Hongtao, Li, Yanping, Zhang, Lihu, Ma, Linwei, Meng, Li, Sun, Xiulan, Qin, Hongbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572074/ https://www.ncbi.nlm.nih.gov/pubmed/31137633 http://dx.doi.org/10.3390/molecules24101993 |
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