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High-Throughput Dissolution/Permeation Screening—A 96-Well Two-Compartment Microplate Approach

Early formulation screening can alleviate development of advanced oral drug formulations, such as amorphous solid dispersions (ASDs). Traditionally, dissolution is used to predict ASD performance. Here, a high-throughput approach is described that simultaneously screens drug dissolution and permeati...

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Detalles Bibliográficos
Autores principales: Jacobsen, Ann-Christin, Krupa, Anna, Brandl, Martin, Bauer-Brandl, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572106/
https://www.ncbi.nlm.nih.gov/pubmed/31083433
http://dx.doi.org/10.3390/pharmaceutics11050227