Cargando…

An Improved Method for the Synthesis of Butein Using SOCl(2)/EtOH as Catalyst and Deciphering Its Inhibition Mechanism on Xanthine Oxidase

Butein (3,4,2′,4′-tetrahydroxychalcone) belongs to the chalcone family of flavonoids and possesses various biological activities. In this study, butein was synthesized through aldol condensation catalyzed by thionyl chloride (SOCl(2))/ethyl alcohol (EtOH) for the first time. The optimal reaction con...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Yu-Xue, Sun, Shi-Wei, Liu, Yang, Li, Yan, Liu, Xiao-Hong, Wang, Wei, Zhang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572126/
https://www.ncbi.nlm.nih.gov/pubmed/31117192
http://dx.doi.org/10.3390/molecules24101948