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An Improved Method for the Synthesis of Butein Using SOCl(2)/EtOH as Catalyst and Deciphering Its Inhibition Mechanism on Xanthine Oxidase
Butein (3,4,2′,4′-tetrahydroxychalcone) belongs to the chalcone family of flavonoids and possesses various biological activities. In this study, butein was synthesized through aldol condensation catalyzed by thionyl chloride (SOCl(2))/ethyl alcohol (EtOH) for the first time. The optimal reaction con...
Autores principales: | Hou, Yu-Xue, Sun, Shi-Wei, Liu, Yang, Li, Yan, Liu, Xiao-Hong, Wang, Wei, Zhang, Shuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572126/ https://www.ncbi.nlm.nih.gov/pubmed/31117192 http://dx.doi.org/10.3390/molecules24101948 |
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