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Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX(3)CL1/CX(3)CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion

Background: Metabolic syndrome is associated with low-grade systemic inflammation, which is a key driver of premature atherosclerosis. We characterized immune cell behavior in metabolic syndrome, its consequences, and the potential involvement of the CX(3)CL1/CX(3)CR1 and CCL2/CCR2 chemokine axes. M...

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Detalles Bibliográficos
Autores principales: Marques, Patrice, Collado, Aida, Martinez-Hervás, Sergio, Domingo, Elena, Benito, Esther, Piqueras, Laura, Real, José T., Ascaso, Juan F., Sanz, Maria-Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572270/
https://www.ncbi.nlm.nih.gov/pubmed/31109070
http://dx.doi.org/10.3390/jcm8050708