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Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes

The propensity of monocytes to migrate into sites of mycobacterium tuberculosis (TB) infection and then become infected themselves makes them potential targets for delivery of drugs intracellularly to the tubercle bacilli reservoir. Conventional TB drugs are less effective because of poor intracellu...

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Detalles Bibliográficos
Autores principales: Afinjuomo, Franklin, Barclay, Thomas G., Parikh, Ankit, Song, Yunmei, Chung, Rosa, Wang, Lixin, Liu, Liang, Hayball, John D., Petrovsky, Nikolai, Garg, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572292/
https://www.ncbi.nlm.nih.gov/pubmed/31121836
http://dx.doi.org/10.3390/pharmaceutics11050243