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Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes
The propensity of monocytes to migrate into sites of mycobacterium tuberculosis (TB) infection and then become infected themselves makes them potential targets for delivery of drugs intracellularly to the tubercle bacilli reservoir. Conventional TB drugs are less effective because of poor intracellu...
Autores principales: | Afinjuomo, Franklin, Barclay, Thomas G., Parikh, Ankit, Song, Yunmei, Chung, Rosa, Wang, Lixin, Liu, Liang, Hayball, John D., Petrovsky, Nikolai, Garg, Sanjay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572292/ https://www.ncbi.nlm.nih.gov/pubmed/31121836 http://dx.doi.org/10.3390/pharmaceutics11050243 |
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