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Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of N-alkyl-acridones and N,N′-dialkyl-9,9′-biacridylidenes

The anticancer activity of acridone derivatives has attracted increasing interest, therefore, a variety of substituted analogs belonging to this family have been developed and evaluated for their anti-cancer properties. A series of N-alkyl-acridones 1–6 and N,N′-dialkyl-9,9′-biacridylidenes 7–12 wit...

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Detalles Bibliográficos
Autores principales: Krokidis, Marios G., Molphy, Zara, Efthimiadou, Eleni K., Kokoli, Marianna, Argyri, Smaragda-Maria, Dousi, Irini, Masi, Annalisa, Papadopoulos, Kyriakos, Kellett, Andrew, Chatgilialoglu, Chryssostomos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572364/
https://www.ncbi.nlm.nih.gov/pubmed/31072044
http://dx.doi.org/10.3390/biom9050177