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Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity

Ticagrelor (TGL), a P2Y(12) receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability. Nanostructured lipid carriers (NLC) are an efficient delivery system for the improvement of...

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Detalles Bibliográficos
Autores principales: Son, Gi-Ho, Na, Young-Guk, Huh, Hyun Wook, Wang, Miao, Kim, Min-Ki, Han, Min-Gu, Byeon, Jin-Ju, Lee, Hong-Ki, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572397/
https://www.ncbi.nlm.nih.gov/pubmed/31071977
http://dx.doi.org/10.3390/pharmaceutics11050222