Cargando…
Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity
Ticagrelor (TGL), a P2Y(12) receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability. Nanostructured lipid carriers (NLC) are an efficient delivery system for the improvement of...
Autores principales: | Son, Gi-Ho, Na, Young-Guk, Huh, Hyun Wook, Wang, Miao, Kim, Min-Ki, Han, Min-Gu, Byeon, Jin-Ju, Lee, Hong-Ki, Cho, Cheong-Weon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572397/ https://www.ncbi.nlm.nih.gov/pubmed/31071977 http://dx.doi.org/10.3390/pharmaceutics11050222 |
Ejemplares similares
-
Strategic approach to developing a self-microemulsifying drug delivery system to enhance antiplatelet activity and bioavailability of ticagrelor
por: Na, Young-Guk, et al.
Publicado: (2019) -
The Delivery Strategy of Paclitaxel Nanostructured Lipid Carrier Coated with Platelet Membrane
por: Bang, Ki-Hyun, et al.
Publicado: (2019) -
Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats
por: Na, Young-Guk, et al.
Publicado: (2019) -
Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
por: El-Helw, Abdel-Rahim M, et al.
Publicado: (2015) -
An EGF- and Curcumin-Co-Encapsulated Nanostructured Lipid Carrier Accelerates Chronic-Wound Healing in Diabetic Rats
por: Lee, Hye-Jin, et al.
Publicado: (2020)