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Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice

Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver disease, is associated with cognitive decline in middle-aged adults, but the mechanisms underlying this association are not clear. We hypothesized that NAFLD would unveil the appearance of brain hypoperfusion in associatio...

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Detalles Bibliográficos
Autores principales: Pinçon, Anthony, De Montgolfier, Olivia, Akkoyunlu, Nilay, Daneault, Caroline, Pouliot, Philippe, Villeneuve, Louis, Lesage, Frédéric, Levy, Bernard I., Thorin-Trescases, Nathalie, Thorin, Éric, Ruiz, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572466/
https://www.ncbi.nlm.nih.gov/pubmed/31130652
http://dx.doi.org/10.3390/metabo9050104