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Cisplatin and Beyond: Molecular Mechanisms of Action and Drug Resistance Development in Cancer Chemotherapy

BACKGROUND: Platinum-based anticancer drugs are widely used in the chemotherapy of human neoplasms. The major obstacle for the clinical use of this class of drugs is the development of resistance and toxicity. It is therefore very important to understand the chemical properties, transport and metabo...

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Detalles Bibliográficos
Autor principal: Makovec, Tomaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572495/
https://www.ncbi.nlm.nih.gov/pubmed/30956230
http://dx.doi.org/10.2478/raon-2019-0018