Penetration Efficiency of Antitumor Agents in Ovarian Cancer Spheroids: The Case of Recombinant Targeted Toxin DARPin-LoPE and the Chemotherapy Drug, Doxorubicin

The efficiency of delivering a therapeutic agent into a tumor is among the crucial factors determining the prospects for its clinical use. This problem is particularly acute in the case of targeted antitumor agents since many of them are high-molecular-weight compounds. In this work, the penetration...

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Detalles Bibliográficos
Autores principales: Sokolova, Evgeniya, Kutova, Olga, Grishina, Alena, Pospelov, Anton, Guryev, Evgeniy, Schulga, Alexey, Deyev, Sergey, Balalaeva, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572593/
https://www.ncbi.nlm.nih.gov/pubmed/31067739
http://dx.doi.org/10.3390/pharmaceutics11050219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572593/
https://www.ncbi.nlm.nih.gov/pubmed/31067739
http://dx.doi.org/10.3390/pharmaceutics11050219

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