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Astragalus Polysaccharide RAP Induces Macrophage Phenotype Polarization to M1 via the Notch Signaling Pathway

Macrophages occur in polarized phenotypes, whose characteristics determine the role they play in tumor growth. The M1 phenotype macrophages promote tumoricidal responses and suppress tumor growth. Our previous study showed that a polysaccharide isolated from Radix Astragali, named RAP, was itself no...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Li, Zhi-Peng, Bian, Zhao-Xiang, Han, Quan-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572696/
https://www.ncbi.nlm.nih.gov/pubmed/31137782
http://dx.doi.org/10.3390/molecules24102016