Subcritical Fluid Chromatography at Sub-Ambient Temperatures for the Chiral Resolution of Ketamine Metabolites with Rapid-Onset Antidepressant Effects

Chiral metabolites of ketamine exerting rapid-onset yet sustained antidepressant effects may be marketed directly in the future, but require chemo- and enantio-selective chromatographic methods for quality assurance and control. The chromatographic behavior of S-/R-ketamine, S-/R-norketamine, S-/R-d...

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Detalles Bibliográficos
Autores principales: Hofstetter, Robert K., Potlitz, Felix, Schulig, Lukas, Kim, Simon, Hasan, Mahmoud, Link, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572699/
https://www.ncbi.nlm.nih.gov/pubmed/31109124
http://dx.doi.org/10.3390/molecules24101927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572699/
https://www.ncbi.nlm.nih.gov/pubmed/31109124
http://dx.doi.org/10.3390/molecules24101927

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