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Depletion of Intestinal Microbiome Partially Rescues Bone Loss in Sickle Cell Disease Male Mice

Osteoporosis or osteopenia are common clinical manifestations of sickle cell disease (SCD) with unclear mechanisms. Since senescence of circulating neutrophil can be modulated by signals derived from intestinal microbiome and neutrophils are abundant in bone marrow and can regulate osteoblasts and o...

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Detalles Bibliográficos
Autores principales: Tavakoli, Sara, Xiao, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572770/
https://www.ncbi.nlm.nih.gov/pubmed/31209247
http://dx.doi.org/10.1038/s41598-019-45270-4