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Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins

Phospholipid homeostasis in biological membranes is essential to maintain functions of organelles such as the endoplasmic reticulum. Phospholipid perturbation has been associated to cellular stress responses. However, in most cases, the implication of membrane lipid changes to homeostatic cellular r...

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Detalles Bibliográficos
Autores principales: Shyu, Peter, Ng, Benjamin S. H., Ho, Nurulain, Chaw, Ruijie, Seah, Yi Ling, Marvalim, Charlie, Thibault, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572771/
https://www.ncbi.nlm.nih.gov/pubmed/31201345
http://dx.doi.org/10.1038/s41598-019-45020-6