Cargando…

Promoter-dependent nuclear RNA degradation ensures cell cycle-specific gene expression

Cell cycle progression depends on phase-specific gene expression. Here we show that the nuclear RNA degradation machinery plays a lead role in promoting cell cycle-dependent gene expression by triggering promoter-dependent co-transcriptional RNA degradation. Single molecule quantification of RNA abu...

Descripción completa

Detalles Bibliográficos
Autores principales: Catala, Mathieu, Abou Elela, Sherif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572803/
https://www.ncbi.nlm.nih.gov/pubmed/31240249
http://dx.doi.org/10.1038/s42003-019-0441-3