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Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers
Chromatin of mammalian nucleus folds into discrete contact enriched regions such as Topologically Associating Domains (TADs). Folding hierarchy and internal organization of TADs is highly dynamic throughout cellular differentiation, and are correlated with gene activation and silencing. To account f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572804/ https://www.ncbi.nlm.nih.gov/pubmed/31201308 http://dx.doi.org/10.1038/s41467-019-10402-x |