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miR-381 modulates human bone mesenchymal stromal cells (BMSCs) osteogenesis via suppressing Wnt signaling pathway during atrophic nonunion development

The osteogenic differentiation of human bone mesenchymal stromal cells (BMSCs) has been considered as a central issue in fracture healing. Wnt signaling could promote BMSC osteogenic differentiation through inhibiting PPARγ. During atrophic nonunion, Wnt signaling-related factors, WNT5A and FZD3 pro...

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Detalles Bibliográficos
Autores principales: Long, Haitao, Zhu, Yong, Lin, Zhangyuan, Wan, Jun, Cheng, Liang, Zeng, Min, Tang, Yifu, Zhao, Ruibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572824/
https://www.ncbi.nlm.nih.gov/pubmed/31209205
http://dx.doi.org/10.1038/s41419-019-1693-z