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Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase

Aerobic methane oxidation is catalyzed by particulate methane monooxygenase (pMMO), a copper-dependent, membrane metalloenzyme composed of subunits PmoA, PmoB, and PmoC. Characterization of the copper active site has been limited by challenges in spectroscopic analysis stemming from the presence of...

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Detalles Bibliográficos
Autores principales: Ro, Soo Y., Schachner, Luis F., Koo, Christopher W., Purohit, Rahul, Remis, Jonathan P., Kenney, Grace E., Liauw, Brandon W., Thomas, Paul M., Patrie, Steven M., Kelleher, Neil L., Rosenzweig, Amy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572826/
https://www.ncbi.nlm.nih.gov/pubmed/31209220
http://dx.doi.org/10.1038/s41467-019-10590-6