Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

Mycobacteria share with other actinomycetes the ability to produce large quantities of triacylglycerol (TAG), which accumulate as intracytoplasmic lipid inclusions (ILI) also known as lipid droplets (LD). Mycobacterium tuberculosis (M. tb), the etiologic agent of tuberculosis, acquires fatty acids f...

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Detalles Bibliográficos
Autores principales: Santucci, Pierre, Johansen, Matt D., Point, Vanessa, Poncin, Isabelle, Viljoen, Albertus, Cavalier, Jean-François, Kremer, Laurent, Canaan, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572852/
https://www.ncbi.nlm.nih.gov/pubmed/31209261
http://dx.doi.org/10.1038/s41598-019-45164-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572852/
https://www.ncbi.nlm.nih.gov/pubmed/31209261
http://dx.doi.org/10.1038/s41598-019-45164-5

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