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Convergent allostery in ribonucleotide reductase

Ribonucleotide reductases (RNRs) use a conserved radical-based mechanism to catalyze the conversion of ribonucleotides to deoxyribonucleotides. Within the RNR family, class Ib RNRs are notable for being largely restricted to bacteria, including many pathogens, and for lacking an evolutionarily mobil...

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Detalles Bibliográficos
Autores principales: Thomas, William C., Brooks, F. Phil, Burnim, Audrey A., Bacik, John-Paul, Stubbe, JoAnne, Kaelber, Jason T., Chen, James Z., Ando, Nozomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572854/
https://www.ncbi.nlm.nih.gov/pubmed/31201319
http://dx.doi.org/10.1038/s41467-019-10568-4