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Using Pseudoenzymes to Probe Evolutionary Design Principles of Enzymes
Enzymes are governed by unique evolutionary design principles as their catalytic sites were shown to induce long-range evolutionary conservation gradients. We have recently used a comparative bioinformatics approach to disentangle structural determinants from other possible determinants of the evolu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572901/ https://www.ncbi.nlm.nih.gov/pubmed/31236007 http://dx.doi.org/10.1177/1176934319855937 |