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PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy

The lung remains an attractive target for the gene therapy of monogenetic diseases such as cystic fibrosis (CF). Despite over 27 clinical trials, there are still very few gene therapy vectors that have shown any improvement in lung function; highlighting the need to develop formulations with improve...

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Detalles Bibliográficos
Autores principales: Osman, Gizem, Rodriguez, Jason, Chan, Sze Yan, Chisholm, Jane, Duncan, Gregg, Kim, Namho, Tatler, Amanda L., Shakesheff, Kevin M., Hanes, Justin, Suk, Jung Soo, Dixon, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573017/
https://www.ncbi.nlm.nih.gov/pubmed/30004000
http://dx.doi.org/10.1016/j.jconrel.2018.07.001