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PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
The lung remains an attractive target for the gene therapy of monogenetic diseases such as cystic fibrosis (CF). Despite over 27 clinical trials, there are still very few gene therapy vectors that have shown any improvement in lung function; highlighting the need to develop formulations with improve...
Autores principales: | Osman, Gizem, Rodriguez, Jason, Chan, Sze Yan, Chisholm, Jane, Duncan, Gregg, Kim, Namho, Tatler, Amanda L., Shakesheff, Kevin M., Hanes, Justin, Suk, Jung Soo, Dixon, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573017/ https://www.ncbi.nlm.nih.gov/pubmed/30004000 http://dx.doi.org/10.1016/j.jconrel.2018.07.001 |
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